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Ketogenic Diet Reverses Diabetic Kidney Disease in Mice

8/1/2013

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Picture
Kimmelsteil Wilson Nodules characteristic of diabetic kidney disease.
One of the major complications of diabetes involves injury to the small blood vessels traveling throughout your body. The excess glucose circulating in your blood stream is toxic to these blood vessels, resulting in damage to the organs or structures they supply. In the kidney, this results in damage to the glomeruli, the microscopic sieves that filter your blood. A new study in mice has shown that a ketogenic diet may reverse this damage: 

"The key to the whole study is that ketones block glucose metabolism," Mobbs said. "Pretty much everybody agrees that diabetic complications are caused by too much glucose metabolism in the cell, so it was kind of an obvious hypothesis that if you can increase ketones long enough, that that would block glucose metabolism and allow the cells to recover from their damage."

Read the whole article here.
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